In 1995, The Cleveland Clinic Foundation performed a study involving a team of cardiologists as well as biologists. The study showed us that people who have low levels of vitamin B6 have an increased chance for developing heart disease.Recently, there have been many more studies on this topic as well. These studies have shown us that high levels of homocysteine are associated with coronary artery disease. Homocysteine is an amino acid in the blood and this increased level can cause heart attacks as well as strokes. Researchers believe that this link between homocysteine and vitamin B6 may even be more profound than the link found between folic acid and homocysteine.